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Onnamide A
Onnamide A is a bioactive natural product found in ''Theonella swinhoei'', a species of marine sponge whose genus is well-known for yielding a diverse set of biologically active natural products, including the swinholides and polytheonamides. It bears structural similarities to the pederins, a family of compounds known to inhibit protein synthesis in eukaryotic cells. Onnamide A and its analogues have attracted academic interest due to their cytotoxicity and potential for combating the growth and proliferation of cancer cells. ==History== Onnamide A was first isolated in 1988 from ''Theonella spp.,'' a genus of marine sponges residing off the coast of Okinawa, Japan, as part of a bioassay aimed at discovering novel marine natural products possessing antiviral activity. Eight analogues possessing similar structure, as well as cytotoxicity were reported in 1992.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Onnamide A」の詳細全文を読む
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